The Comfort Inn Wytheville offers 78 interior corridor rooms. Enjoy our Comfort Sunshine Breakfast each morning to stay the day right. Each of our guest rooms features an In room Coffee maker, hairdryer, iron and board. TV’s with expanded cable and HBO & ESPN. We offer AAA and AARP rates. Our hotel has Free WiFi, a Fitness Center, a Business Center and an Outdoor Pool. Enjoy our expanded breakfast and lobby area for all your traveling needs. Book Now!